Anti-CPEB1 Polyclonal Antibody (HV237014)

价格:

规格：

50ug
100ug

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HV237014

品牌

abinScience

描述

Anti-CPEB1 Polyclonal Antibody (HV237014) is a rabbit polyclonal antibody detecting CPEB1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Pongo abelii, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CPEB1 (Cys311-Lys561).

靶标

CPEB, hCPEB-1, Cytoplasmic polyadenylation element-binding protein 1, CPE-binding protein 1, CPEB1, h-CPEB, CPE-BP1

纯化方式

Purified by antigen affinity column.

Accession号

Q9BZB8

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cytoplasmic polyadenylation element-binding protein 1 (CPEB1) is a ~62 kDa protein. Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation. Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses.

1. Afroz, T. et al. (2014) Genes & development 28, 1498-514. PMID: 24990967

2. Giangarrà, V. et al. (2015) PloS one 10, e0138794. PMID: 26398195

Note

For research use only.

图片

参考文献

产品说明书

Anti-CPEB1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CPEB1 Polyclonal Antibody (HV237014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CPEB1 Polyclonal Antibody (HV237014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价