Anti-TOLLIP Polyclonal Antibody (HV619014)

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概述
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参考文献
产品说明书

概述

货号

HV619014

品牌

abinScience

描述

Anti-TOLLIP Polyclonal Antibody (HV619014) is a rabbit polyclonal antibody detecting TOLLIP in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human TOLLIP (Gln28-Asp261).

靶标

Toll-interacting protein, TOLLIP

纯化方式

Purified by antigen affinity column.

Accession号

Q9H0E2

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Toll-interacting protein (TOLLIP) is a ~30 kDa protein. Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates.

1. Burns, K. et al. (2000) Nature cell biology 2, 346-51. PMID: 10854325

2. Zhang, G. et al. (2002) The Journal of biological chemistry 277, 7059-65. PMID: 11751856

3. Lu, K. et al. (2014) Cell 158, 549-63. PMID: 25042851

4. Katoh, Y. et al. (2004) The Journal of biological chemistry 279, 24435-43. PMID: 15047686

5. Xiao, S. et al. (2015) Structure (London, England : 1993) 23, 1910-1920. PMID: 26320582

Note

For research use only.

图片

参考文献

产品说明书

Anti-TOLLIP Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-TOLLIP Polyclonal Antibody (HV619014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-TOLLIP Polyclonal Antibody (HV619014)

概述

图片

参考文献

产品说明书

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