

| 货号 | ARO-A13651 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-TOLLIP Polyclonal Antibody (ARO-A13651) is a rabbit polyclonal antibody detecting Toll-interacting protein, TOLLIP in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bos taurus, Chicken.
Highlights
|
| 种属反应性 | Human, Mouse, Rat, Bos taurus, Chicken |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human TOLLIP (Gln28-Asp261). |
| 靶标 | Toll-interacting protein, TOLLIP |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9H0E2 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Toll-interacting protein (TOLLIP) is a ~30 kDa protein. Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. 1. Burns, K. et al. (2000) Nature cell biology 2, 346-51. PMID: 10854325 2. Zhang, G. et al. (2002) The Journal of biological chemistry 277, 7059-65. PMID: 11751856 3. Lu, K. et al. (2014) Cell 158, 549-63. PMID: 25042851 4. Katoh, Y. et al. (2004) The Journal of biological chemistry 279, 24435-43. PMID: 15047686 5. Xiao, S. et al. (2015) Structure (London, England : 1993) 23, 1910-1920. PMID: 26320582 |
| Note | For research use only. |

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