Anti-CLEC1B Polyclonal Antibody (HV788014)

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概述
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参考文献
产品说明书

概述

货号

HV788014

品牌

abinScience

描述

Anti-CLEC1B Polyclonal Antibody (HV788014) is a rabbit polyclonal antibody detecting CLEC1B in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CLEC1B (Val56-Pro229).

靶标

CLEC1B, C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC2, CLEC-2

纯化方式

Purified by antigen affinity column.

Accession号

Q9P126

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

C-type lectin domain family 1 member B (CLEC1B) is a ~26 kDa protein. C-type lectin-like receptor that serves as a platelet receptor for the lymphatic endothelial marker PDPN. Plays an essential role in blood/lymphatic vessel separation and thrombus formation through homophilic association. Acts as a negative regulator of lymphatic endothelial cell behavior by inhibiting proliferation, migration, and tube formation. Upon ligand binding, triggers a signaling cascade via sequential activation of SRC and SYK tyrosine kinases, leading to activation of PLCG2. Through this pathway, mediates platelet adhesion, aggregation, and secretion in response to PDPN-expressing cells.

1. Christou, CM. et al. (2008) The Biochemical journal 411, 133-40. PMID: 18215137

2. Osada, M. et al. (2012) The Journal of biological chemistry 287, 22241-52. PMID: 22556408

3. Mori, J. et al. (2008) The Journal of biological chemistry 283, 35419-27. PMID: 18955485

Note

For research use only.

图片

参考文献

产品说明书

Anti-CLEC1B Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CLEC1B Polyclonal Antibody (HV788014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CLEC1B Polyclonal Antibody (HV788014)

概述

图片

参考文献

产品说明书

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