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Anti-CLEC1B Polyclonal Antibody (ARO-A13614)

概述
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参考文献

概述

货号	ARO-A13614
品牌	ProteoGenix
描述	Anti-CLEC1B Polyclonal Antibody (ARO-A13614) is a rabbit polyclonal antibody detecting CLEC1B, C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC2, CLEC-2 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
同种型	IgG
克隆类型	Polyclonal
免疫原	E. coli - derived recombinant Human CLEC1B (Val56-Pro229).
靶标	CLEC1B, C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC2, CLEC-2
纯化方式	Purified by antigen affinity column.
Accession号	Q9P126
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	C-type lectin domain family 1 member B (CLEC1B) is a ~26 kDa protein. C-type lectin-like receptor that serves as a platelet receptor for the lymphatic endothelial marker PDPN. Plays an essential role in blood/lymphatic vessel separation and thrombus formation through homophilic association. Acts as a negative regulator of lymphatic endothelial cell behavior by inhibiting proliferation, migration, and tube formation. Upon ligand binding, triggers a signaling cascade via sequential activation of SRC and SYK tyrosine kinases, leading to activation of PLCG2. Through this pathway, mediates platelet adhesion, aggregation, and secretion in response to PDPN-expressing cells. 1. Christou, CM. et al. (2008) The Biochemical journal 411, 133-40. PMID: 18215137 2. Osada, M. et al. (2012) The Journal of biological chemistry 287, 22241-52. PMID: 22556408 3. Mori, J. et al. (2008) The Journal of biological chemistry 283, 35419-27. PMID: 18955485
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-CLEC1B Polyclonal Antibody

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