Anti-SKP1 Polyclonal Antibody (HX846014)

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100ug

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概述
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产品说明书

概述

货号

HX846014

品牌

abinScience

描述

Anti-SKP1 Polyclonal Antibody (HX846014) is a rabbit polyclonal antibody detecting SKP1 in ELISA, IHC, WB. Suitable for Bovine, Cavia porcellus, Chicken, Human, and Macaca fascicularis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human SKP1 (Met1-Lys163).

靶标

p19A, Organ of Corti protein 2, EMC19, SKP1, Organ of Corti protein II, OCP2, OCP-2, RNA polymerase II elongation factor-like protein, Cyclin-A/CDK2-associated protein p19, OCP-II, p19skp1, TCEB1L, S-phase kinase-associated protein 1, SIII, Transcription elongation factor B polypeptide 1-like, SKP1A

纯化方式

Purified by antigen affinity column.

Accession号

P63208

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

S-phase kinase-associated protein 1 (SKP1) is a ~18 kDa protein. Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA.

1. Man, X. et al. (2015) European journal of cell biology 94, 162-72. PMID: 25704143

2. Hopf, LVM. et al. (2022) Nature structural & molecular biology 29, 854-862. PMID: 35982156

3. Cao, Y. et al. (2023) The EMBO journal 42, e113033. PMID: 36896912

Note

For research use only.

图片

参考文献

产品说明书

Anti-SKP1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SKP1 Polyclonal Antibody (HX846014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SKP1 Polyclonal Antibody (HX846014)

概述

图片

参考文献

产品说明书

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