Anti-Human LILRB2/CD85d/ILT4 Polyclonal Antibody (HV255014)

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概述
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参考文献
产品说明书

概述

货号

HV255014

品牌

abinScience

描述

Anti-CD85d/LILRB2 Polyclonal Antibody (HV255014) is a rabbit polyclonal antibody detecting LILRB2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CD85d/LILRB2 (Leu53-Val255).

靶标

CD85 antigen-like family member D, Monocyte/macrophage immunoglobulin-like receptor 10, MIR-10, ILT4, LIR-2, ILT-4, Immunoglobulin-like transcript 4, MIR10, CD85d, Leukocyte immunoglobulin-like receptor subfamily B member 2, Leukocyte immunoglobulin-like receptor 2, LIR2, LILRB2

纯化方式

Purified by antigen affinity column.

Accession号

Q8N423

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Leukocyte immunoglobulin-like receptor subfamily B member 2 (CD85d/LILRB2) is a ~65 kDa protein. Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance. Competes with CD8A for binding to class I MHC antigens.

1. Lepin, EJ. et al. (2000) European journal of immunology 30, 3552-61. PMID: 11169396

2. Shiroishi, M. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 8856-61. PMID: 12853576

3. Shiroishi, M. et al. (2006) The Journal of biological chemistry 281, 10439-47. PMID: 16455647

4. Gregori, S. et al. (2010) Blood 116, 935-44. PMID: 20448110

5. Köstlin, N. et al. (2017) European journal of immunology 47, 374-384. PMID: 27859042

6. Chang, CC. et al. (2002) Nature immunology 3, 237-43. PMID: 11875462

8. Fanger, NA. et al. (1998) European journal of immunology 28, 3423-34. PMID: 9842885

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human LILRB2/CD85d/ILT4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LILRB2/CD85d/ILT4 Polyclonal Antibody (HV255014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LILRB2/CD85d/ILT4 Polyclonal Antibody (HV255014)

概述

图片

参考文献

产品说明书

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