Anti-Human GSDMD Polyclonal Antibody (HX874014)

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50ug
100ug

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概述
图片
参考文献
产品说明书

概述

货号

HX874014

品牌

abinScience

描述

Anti-Human GSDMD Polyclonal Antibody (HX874014) is a rabbit polyclonal antibody detecting GSDMD in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human GSDMD (Pro278-His484).

靶标

GSDMD-CT, hGSDMD-NTD, Gasdermin domain-containing protein 1, Gasdermin-D, DFNA5L, GSDMD-NT, hGSDMD-CTD, GSDMDC1, GSDMD

纯化方式

Purified by antigen affinity column.

Accession号

P57764

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Gasdermin-D (GSDMD) is a ~52 kDa protein. Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis.

1. Shi, J. et al. (2015) Nature 526, 660-5. PMID: 26375003

2. Kayagaki, N. et al. (2015) Nature 526, 666-71. PMID: 26375259

3. Ding, J. et al. (2016) Nature 535, 111-6. PMID: 27281216

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-GSDMD polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
Lane 2: THP-1 cell lysate

参考文献

产品说明书

Anti-Human GSDMD Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GSDMD Polyclonal Antibody (HX874014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GSDMD Polyclonal Antibody (HX874014)

概述

图片

参考文献

产品说明书

相关产品推荐

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