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Anti-Human GSDMD Polyclonal Antibody (ARO-A13505)

概述
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参考文献

概述

货号	ARO-A13505
品牌	ProteoGenix
描述	Anti-Human GSDMD Polyclonal Antibody (ARO-A13505) is a rabbit polyclonal antibody detecting GSDMD-CT, hGSDMD-NTD, Gasdermin domain-containing protein 1, Gasdermin-D, DFNA5L, GSDMD-NT, hGSDMD-CTD, GSDMDC1, GSDMD in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
同种型	IgG
克隆类型	Polyclonal
免疫原	E. coli - derived recombinant Human GSDMD (Pro278-His484).
靶标	GSDMD-CT, hGSDMD-NTD, Gasdermin domain-containing protein 1, Gasdermin-D, DFNA5L, GSDMD-NT, hGSDMD-CTD, GSDMDC1, GSDMD
纯化方式	Purified by antigen affinity column.
Accession号	P57764
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Gasdermin-D (GSDMD) is a ~52 kDa protein. Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis. 1. Shi, J. et al. (2015) Nature 526, 660-5. PMID: 26375003 2. Kayagaki, N. et al. (2015) Nature 526, 666-71. PMID: 26375259 3. Ding, J. et al. (2016) Nature 535, 111-6. PMID: 27281216
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human GSDMD Polyclonal Antibody

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