

| 货号 | HP089014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human STAMBPL1/AMSHLP Polyclonal Antibody (HP089014) is a rabbit polyclonal antibody detecting STAMBPL1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Pongo abelii.
Highlights
| ||||||||
| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human STAMBPL1/AMSHLP (Arg267-Arg436). | ||||||||
| 靶标 | AMSHLP, AMSH-LP, AMSH-like protease, STAMBPL1, STAM-binding protein-like 1, KIAA1373 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q96FJ0 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | AMSH-like protease (STAMBPL1/AMSHLP) is a ~49 kDa protein. Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex. Does not cleave 'Lys-48'-linked polyubiquitin chains. 1. Sato, Y. et al. (2008) Nature 455, 358-62. PMID: 18758443 2. Wang, D. et al. (2022) Molecular cell 82, 770-784.e9. PMID: 35114100 | ||||||||
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理