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Anti-Human STAMBPL1/AMSHLP Polyclonal Antibody (ARO-A12665)

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概述
货号ARO-A12665
品牌ProteoGenix
描述
Anti-Human STAMBPL1/AMSHLP Polyclonal Antibody (ARO-A12665) is a rabbit polyclonal antibody detecting AMSHLP, AMSH-LP, AMSH-like protease, STAMBPL1, STAM-binding protein-like 1, KIAA1373 in ELISA, IHC, WB. Suitable for Human, Mouse, Pongo abelii.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Pongo abelii
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human STAMBPL1/AMSHLP (Arg267-Arg436).
靶标AMSHLP, AMSH-LP, AMSH-like protease, STAMBPL1, STAM-binding protein-like 1, KIAA1373
纯化方式Purified by antigen affinity column.
Accession号Q96FJ0
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

AMSH-like protease (STAMBPL1/AMSHLP) is a ~49 kDa protein. Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex. Does not cleave 'Lys-48'-linked polyubiquitin chains.

1. Sato, Y. et al. (2008) Nature 455, 358-62. PMID: 18758443
2. Wang, D. et al. (2022) Molecular cell 82, 770-784.e9. PMID: 35114100
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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