Anti-Human RB1CC1 Polyclonal Antibody (HP312014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HP312014

品牌

abinScience

描述

Anti-Human RB1CC1 Polyclonal Antibody (HP312014) is a rabbit polyclonal antibody detecting RB1CC1 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human RB1CC1 (Glu1447-Val1594).

靶标

FAK family kinase-interacting protein of 200 kDa, RB1CC1, FIP200, RBICC, RB1-inducible coiled-coil protein 1, KIAA0203

纯化方式

Purified by antigen affinity column.

Accession号

Q8TDY2

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

RB1-inducible coiled-coil protein 1 (RB1CC1) is a ~183 kDa protein. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy. Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis. Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways.

1. Morselli, E. et al. (2011) Cell cycle (Georgetown, Tex.) 10, 2763-9. PMID: 21775823

2. Nishimura, T. et al. (2013) EMBO reports 14, 284-91. PMID: 23392225

3. Ueda, H. et al. (2000) The Journal of cell biology 149, 423-30. PMID: 10769033

4. Abbi, S. et al. (2002) Molecular biology of the cell 13, 3178-91. PMID: 12221124

5. Chano, T. et al. (2002) Gene 291, 29-34. PMID: 12095676

6. Kontani, K. et al. (2003) International journal of molecular medicine 12, 767-9. PMID: 14533007

7. Chano, T. et al. (2002) The American journal of pathology 161, 359-64. PMID: 12163359

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human RB1CC1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RB1CC1 Polyclonal Antibody (HP312014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RB1CC1 Polyclonal Antibody (HP312014)

概述

图片

参考文献

产品说明书

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