Anti-Human CBS Polyclonal Antibody (HW451014)

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概述
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参考文献
产品说明书

概述

货号

HW451014

品牌

abinScience

描述

Anti-Human CBS Polyclonal Antibody (HW451014) is a rabbit polyclonal antibody detecting CBS in ELISA, IHC, WB. Suitable for Human, Mouse, and Macaca fascicularis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human CBS (Lys72-Lys551).

靶标

Serine sulfhydrase, CBS, Cystathionine beta-synthase, Beta-thionase

纯化方式

Purified by antigen affinity column.

Accession号

P35520

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cystathionine beta-synthase (CBS) is a ~60 kDa protein. Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.

1. Kozich, V. et al. (2010) Human mutation 31, 809-19. PMID: 20506325

2. Mendes, MI. et al. (2014) Journal of inherited metabolic disease 37, 245-54. PMID: 23974653

3. Casique, L. et al. (2013) Gene 531, 117-24. PMID: 23981774

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human CBS Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CBS Polyclonal Antibody (HW451014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CBS Polyclonal Antibody (HW451014)

概述

图片

参考文献

产品说明书

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