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Anti-Human CBS Polyclonal Antibody (PTX20096)

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概述
货号PTX20096
品牌ProteoGenix
描述
Anti-Human CBS Polyclonal Antibody (PTX20096) is a rabbit polyclonal antibody detecting Serine sulfhydrase, CBS, Cystathionine beta-synthase, Beta-thionase in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CBS (Lys72-Lys551).
靶标Serine sulfhydrase, CBS, Cystathionine beta-synthase, Beta-thionase
纯化方式Purified by antigen affinity column.
Accession号P35520
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Cystathionine beta-synthase (CBS) is a ~60 kDa protein. Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.

1. Kozich, V. et al. (2010) Human mutation 31, 809-19. PMID: 20506325
2. Mendes, MI. et al. (2014) Journal of inherited metabolic disease 37, 245-54. PMID: 23974653
3. Casique, L. et al. (2013) Gene 531, 117-24. PMID: 23981774
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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