

| 货号 | HP599014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human BBC3 Polyclonal Antibody (HP599014) is a rabbit polyclonal antibody detecting BBC3 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human BBC3 (Glu130-Pro180). | ||||||||
| 靶标 | p53 up-regulated modulator of apoptosis, BBC3, JFY-1, PUMA, Bcl-2-binding component 3, isoforms 1/2 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9BXH1 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Bcl-2-binding component 3, isoforms 1/2 (BBC3) is a ~20 kDa protein. Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Promotes partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53, releasing the bound p53/TP53 to induce apoptosis. Regulates ER stress-induced neuronal apoptosis. 1. Yu, J. et al. (2001) Molecular cell 7, 673-82. PMID: 11463391 2. Follis, AV. et al. (2013) Nature chemical biology 9, 163-8. PMID: 23340338 | ||||||||
| Note | For research use only. |

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