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Anti-Human BBC3 Polyclonal Antibody (ARO-A12626)

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概述
货号ARO-A12626
品牌ProteoGenix
描述
Anti-Human BBC3 Polyclonal Antibody (ARO-A12626) is a rabbit polyclonal antibody detecting p53 up-regulated modulator of apoptosis, BBC3, JFY-1, PUMA, Bcl-2-binding component 3, isoforms 1/2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human BBC3 (Glu130-Pro180).
靶标p53 up-regulated modulator of apoptosis, BBC3, JFY-1, PUMA, Bcl-2-binding component 3, isoforms 1/2
纯化方式Purified by antigen affinity column.
Accession号Q9BXH1
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Bcl-2-binding component 3, isoforms 1/2 (BBC3) is a ~20 kDa protein. Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Promotes partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53, releasing the bound p53/TP53 to induce apoptosis. Regulates ER stress-induced neuronal apoptosis.

1. Yu, J. et al. (2001) Molecular cell 7, 673-82. PMID: 11463391
2. Follis, AV. et al. (2013) Nature chemical biology 9, 163-8. PMID: 23340338
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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