

| 货号 | HC698024 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-KIF5A Polyclonal Antibody (HC698024) is a rabbit polyclonal antibody detecting KIF5A in ELISA, IHC, WB. Suitable for Human, Mouse, Pongo abelii, and Rat.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human KIF5A (Met1-Ala331). | ||||||||
| 靶标 | NKHC1, KIF5A, Kinesin heavy chain isoform 5A, Neuronal kinesin heavy chain, Kinesin heavy chain neuron-specific 1, NKHC | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q12840 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Kinesin heavy chain isoform 5A (KIF5A) is a ~117 kDa protein. Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. | ||||||||
| Note | For research use only. |

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