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Anti-KIF5A Polyclonal Antibody (ARO-A12598)

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概述
货号ARO-A12598
品牌ProteoGenix
描述
Anti-KIF5A Polyclonal Antibody (ARO-A12598) is a rabbit polyclonal antibody detecting NKHC1, KIF5A, Kinesin heavy chain isoform 5A, Neuronal kinesin heavy chain, Kinesin heavy chain neuron-specific 1, NKHC in ELISA, IHC, WB. Suitable for Human, Mouse, Pongo abelii, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Pongo abelii, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human KIF5A (Met1-Ala331).
靶标NKHC1, KIF5A, Kinesin heavy chain isoform 5A, Neuronal kinesin heavy chain, Kinesin heavy chain neuron-specific 1, NKHC
纯化方式Purified by antigen affinity column.
Accession号Q12840
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Kinesin heavy chain isoform 5A (KIF5A) is a ~117 kDa protein. Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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