

| 货号 | HF712014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human RNASEH1 Polyclonal Antibody (HF712014) is a rabbit polyclonal antibody detecting RNASEH1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RNASEH1 (Asp138-Asp286). | ||||||||
| 靶标 | RNase H1, RNASEH1, RNH1, Ribonuclease H type II, Ribonuclease H1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O60930 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ribonuclease H1 (RNASEH1) is a ~32 kDa protein. Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. 1. Wu, H. et al. (1999) The Journal of biological chemistry 274, 28270-8. PMID: 10497183 2. Skourti-Stathaki, K. et al. (2011) Molecular cell 42, 794-805. PMID: 21700224 | ||||||||
| Note | For research use only. |

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