

| 货号 | ARO-A12588 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human RNASEH1 Polyclonal Antibody (ARO-A12588) is a rabbit polyclonal antibody detecting RNase H1, RNASEH1, RNH1, Ribonuclease H type II, Ribonuclease H1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human RNASEH1 (Asp138-Asp286). |
| 靶标 | RNase H1, RNASEH1, RNH1, Ribonuclease H type II, Ribonuclease H1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | O60930 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Ribonuclease H1 (RNASEH1) is a ~32 kDa protein. Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. 1. Wu, H. et al. (1999) The Journal of biological chemistry 274, 28270-8. PMID: 10497183 2. Skourti-Stathaki, K. et al. (2011) Molecular cell 42, 794-805. PMID: 21700224 |
| Note | For research use only. |

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