Anti-Human TNFAIP8L2 Polyclonal Antibody (HP334014)

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概述
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参考文献
产品说明书

概述

货号

HP334014

品牌

abinScience

描述

Anti-Human TNFAIP8L2 Polyclonal Antibody (HP334014) is a rabbit polyclonal antibody detecting TNFAIP8L2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Callithrix jacchus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human TNFAIP8L2 (Met1-Leu184).

靶标

TNF alpha-induced protein 8-like protein 2, Tumor necrosis factor alpha-induced protein 8-like protein 2, TNFAIP8-like protein 2, Inflammation factor protein 20, TIPE2, TNFAIP8L2

纯化方式

Purified by antigen affinity column.

Accession号

Q6P589

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Tumor necrosis factor alpha-induced protein 8-like protein 2 (TNFAIP8L2) is a ~20 kDa protein. Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Plays a regulatory role in the Toll-like signaling pathway by determining the strength of LPS-induced signaling and gene expression. Inhibits TCR-mediated T-cell activation and negatively regulate T-cell function to prevent hyperresponsiveness. Also inhibits autolysosome formation via negatively modulating MTOR activation by interacting with RAC1 and promoting the disassociation of the RAC1-MTOR complex. Plays an essential role in NK-cell biology by acting as a checkpoint and displaying an expression pattern correlating with NK-cell maturation process and by negatively regulating NK-cell maturation and antitumor immunity.

1. Suo, LG. et al. (2016) Molecular immunology 73, 46-52. PMID: 27043859

2. Lou, Y. et al. (2020) Journal of immunology (Baltimore, Md. : 1950) 204, 2122-2132. PMID: 32188758

3. Li, W. et al. (2021) Autophagy 17, 1410-1425. PMID: 32460619

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human TNFAIP8L2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TNFAIP8L2 Polyclonal Antibody (HP334014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TNFAIP8L2 Polyclonal Antibody (HP334014)

概述

图片

参考文献

产品说明书

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