Anti-Human TUT4 Polyclonal Antibody (HP132014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HP132014

品牌

abinScience

描述

Anti-Human TUT4 Polyclonal Antibody (HP132014) is a rabbit polyclonal antibody detecting TUT4 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human TUT4 (Glu246-Asp370).

靶标

TUTase 4, KIAA0191, TUT4, ZCCHC11, Terminal uridylyltransferase 4, Zinc finger CCHC domain-containing protein 11

纯化方式

Purified by antigen affinity column.

Accession号

Q5TAX3

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Terminal uridylyltransferase 4 (TUT4) is a ~185 kDa protein. Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Essential for both oocyte maturation and fertility. Through 3' terminal uridylation of mRNA, sculpts, with TUT7, the maternal transcriptome by eliminating transcripts during oocyte growth. Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also functions as an integral regulator of microRNA biogenesis using 3 different uridylation mechanisms.

1. Lim, J. et al. (2014) Cell 159, 1365-76. PMID: 25480299

2. Yamashita, S. et al. (2019) Nature communications 10, 1960. PMID: 31036859

3. Kim, B. et al. (2015) The EMBO journal 34, 1801-15. PMID: 25979828

4. Heo, I. et al. (2009) Cell 138, 696-708. PMID: 19703396

5. Minoda, Y. et al. (2006) Biochemical and biophysical research communications 344, 1023-30. PMID: 16643855

6. Mullen, TE. et al. (2008) Genes & development 22, 50-65. PMID: 18172165

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human TUT4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TUT4 Polyclonal Antibody (HP132014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TUT4 Polyclonal Antibody (HP132014)

概述

图片

参考文献

产品说明书

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