Anti-Human PANX1 Polyclonal Antibody (HP450014)

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50ug
100ug

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HP450014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human PANX1 (Ser236-Gln274).

MRS1, Pannexin-1, PANX1

Purified by antigen affinity column.

Accession号

Q96RD7

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Pannexin-1 (PANX1) is a ~48 kDa protein. Ion channel involved in a variety of physiological functions such as blood pressure regulation, apoptotic cell clearance and oogenesis. Forms anion-selective channels with relatively low conductance and an order of permeabilities: nitrate>iodide>chlroride>>aspartate=glutamate=gluconate. Can release ATP upon activation through phosphorylation or cleavage at C-terminus. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.

1. Bao, L. et al. (2004) FEBS letters 572, 65-8. PMID: 15304325

2. Vanden Abeele, F. et al. (2006) The Journal of cell biology 174, 535-46. PMID: 16908669

3. Bunse, S. et al. (2010) The Journal of biological chemistry 285, 38444-52. PMID: 20829356

4. Chekeni, FB. et al. (2010) Nature 467, 863-7. PMID: 20944749

5. Sang, Q. et al. (2019) Science translational medicine 11. PMID: 30918116

6. Medina, CB. et al. (2020) Nature 580, 130-135. PMID: 32238926

For research use only.

产品说明书

Anti-Human PANX1 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PANX1 Polyclonal Antibody (HP450014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PANX1 Polyclonal Antibody (HP450014)

概述

图片

参考文献

产品说明书

相关产品推荐

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