Anti-Human USP21 Polyclonal Antibody (HP890014)

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规格：

50ug
100ug

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HP890014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human USP21 (Thr220-Leu565).

Ubiquitin carboxyl-terminal hydrolase 21, Ubiquitin thioesterase 21, Deubiquitinating enzyme 21, USP21, Ubiquitin-specific-processing protease 21, USP23

Purified by antigen affinity column.

Accession号

Q9UK80

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Ubiquitin carboxyl-terminal hydrolase 21 (USP21) is a ~62 kDa protein. Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination. Deubiquitinates BAZ2A/TIP5 leading to its stabilization. Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.

1. Khan, A. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 8338-43. PMID: 26100909

2. Gong, L. et al. (2000) The Journal of biological chemistry 275, 14212-6. PMID: 10799498

3. Garshott, DM. et al. (2020) eLife 9. PMID: 32011234

For research use only.

产品说明书

Anti-Human USP21 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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Anti-Human USP21 Polyclonal Antibody (HP890014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human USP21 Polyclonal Antibody (HP890014)

概述

图片

参考文献

产品说明书

相关产品推荐

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