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Anti-Human USP21 Polyclonal Antibody (ARO-A12222)

概述
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参考文献

概述

货号	ARO-A12222
品牌	ProteoGenix
描述	Anti-Human USP21 Polyclonal Antibody (ARO-A12222) is a rabbit polyclonal antibody detecting Ubiquitin carboxyl-terminal hydrolase 21, Ubiquitin thioesterase 21, Deubiquitinating enzyme 21, USP21, Ubiquitin-specific-processing protease 21, USP23 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human USP21 (Thr220-Leu565).
靶标	Ubiquitin carboxyl-terminal hydrolase 21, Ubiquitin thioesterase 21, Deubiquitinating enzyme 21, USP21, Ubiquitin-specific-processing protease 21, USP23
纯化方式	Purified by antigen affinity column.
Accession号	Q9UK80
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Ubiquitin carboxyl-terminal hydrolase 21 (USP21) is a ~62 kDa protein. Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination. Deubiquitinates BAZ2A/TIP5 leading to its stabilization. Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates. 1. Khan, A. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 8338-43. PMID: 26100909 2. Gong, L. et al. (2000) The Journal of biological chemistry 275, 14212-6. PMID: 10799498 3. Garshott, DM. et al. (2020) eLife 9. PMID: 32011234
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human USP21 Polyclonal Antibody

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