Anti-Human SENP3 Polyclonal Antibody (HP948014)

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规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

HP948014

abinScience

种属反应性

Human, Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human SENP3 (Glu311-Val574).

Sentrin-specific protease 3, Sentrin/SUMO-specific protease SENP3, SENP3, SUSP3, SUMO-1-specific protease 3, SSP3

Purified by antigen affinity column.

Accession号

Q9H4L4

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Sentrin-specific protease 3 (SENP3) is a ~65 kDa protein. Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1.

1. Gong, L. et al. (2006) The Journal of biological chemistry 281, 15869-77. PMID: 16608850

2. Gao, SS. et al. (2020) Science advances 6, eaba7822. PMID: 32832608

3. Zhang, T. et al. (2022) Nature communications 13, 5133. PMID: 36050397

4. Grégoire, S. et al. (2005) Molecular and cellular biology 25, 2273-87. PMID: 15743823

5. Klein, UR. et al. (2009) Molecular biology of the cell 20, 410-8. PMID: 18946085

6. Huang, C. et al. (2009) The EMBO journal 28, 2748-62. PMID: 19680224

7. Yun, C. et al. (2008) The Journal of cell biology 183, 589-95. PMID: 19015314

8. Haindl, M. et al. (2008) EMBO reports 9, 273-9. PMID: 18259216

9. Fanis, P. et al. (2012) Molecular & cellular proteomics : MCP 11, 1263-73. PMID: 22872859

For research use only.

产品说明书

Anti-Human SENP3 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SENP3 Polyclonal Antibody (HP948014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SENP3 Polyclonal Antibody (HP948014)

概述

图片

参考文献

产品说明书

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