Anti-Human ZNF410 Polyclonal Antibody (HP086014)

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50ug
100ug

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概述
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参考文献
产品说明书

HP086014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human ZNF410 (Arg76-Ser191).

ZNF410, APA1, Another partner for ARF 1, Zinc finger protein 410, Zinc finger protein APA-1

Purified by antigen affinity column.

Accession号

Q86VK4

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Zinc finger protein 410 (ZNF410) is a ~52 kDa protein. Transcription factor that binds to the sequence motif 5'-CATCCCATAATA-3', and is specifically required to silence expression of fetal hemoglobin in adult erythroid cells. Prevents expression of fetal hemoglobin genes HBG1 and HBG2 through CHD4: acts as a direct transcriptional activator of CHD4, a central component of the NuRD complex that represses transcription of fetal hemoglobin genes HBG1 and HBG2 in erythroid cells. May also activate transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence. May activate transcription of the gap junction gene GJC1, perhaps in response to increasing glucose. However, recent studies suggest that ZNF410 is dedicated to regulate expression of a single gene: CHD4.

1. Lan, X. et al. (2021) Molecular cell 81, 239-254.e8. PMID: 33301730

2. Vinjamur, DS. et al. (2021) Nature genetics 53, 719-728. PMID: 33859416

3. Benanti, JA. et al. (2002) Molecular and cellular biology 22, 7385-97. PMID: 12370286

4. Chen, Y. et al. (2018) Journal of cellular physiology 234, 606-618. PMID: 30078215

For research use only.

产品说明书

Anti-Human ZNF410 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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实验相关试剂

Anti-Human ZNF410 Polyclonal Antibody (HP086014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ZNF410 Polyclonal Antibody (HP086014)

概述

图片

参考文献

产品说明书

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