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Anti-Human ABCA7 Polyclonal Antibody (HP315014)

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  • 100ug
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概述
货号HP315014
品牌abinScience
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ABCA7 (Asp1773-Asp2121).
靶标Macrophage ABC transporter, ABCA-SSN, ATP-binding cassette sub-family A member 7, Autoantigen SS-N, Phospholipid-transporting ATPase ABCA7, ABCA7
纯化方式Purified by antigen affinity column.
Accession号Q8IZY2
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Phospholipid-transporting ATPase ABCA7 is a ~234 kDa protein. Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP. Transports preferentially phosphatidylserine over phosphatidylcholine. Plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux.

1. Quazi, F. et al. (2013) The Journal of biological chemistry 288, 34414-26. PMID: 24097981
2. Wang, N. et al. (2003) The Journal of biological chemistry 278, 42906-12. PMID: 12917409
3. Kielar, D. et al. (2003) The Journal of investigative dermatology 121, 465-74. PMID: 12925201
4. Abe-Dohmae, S. et al. (2004) The Journal of biological chemistry 279, 604-11. PMID: 14570867
5. Ikeda, Y. et al. (2003) Biochemical and biophysical research communications 311, 313-8. PMID: 14592415
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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