

| 货号 | PTX20215 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human ABCA7 Polyclonal Antibody (PTX20215) is a rabbit polyclonal antibody detecting Macrophage ABC transporter, ABCA-SSN, ATP-binding cassette sub-family A member 7, Autoantigen SS-N, Phospholipid-transporting ATPase ABCA7, ABCA7 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human ABCA7 (Asp1773-Asp2121). |
| 靶标 | Macrophage ABC transporter, ABCA-SSN, ATP-binding cassette sub-family A member 7, Autoantigen SS-N, Phospholipid-transporting ATPase ABCA7, ABCA7 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q8IZY2 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Phospholipid-transporting ATPase ABCA7 is a ~234 kDa protein. Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP. Transports preferentially phosphatidylserine over phosphatidylcholine. Plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. 1. Quazi, F. et al. (2013) The Journal of biological chemistry 288, 34414-26. PMID: 24097981 2. Wang, N. et al. (2003) The Journal of biological chemistry 278, 42906-12. PMID: 12917409 3. Kielar, D. et al. (2003) The Journal of investigative dermatology 121, 465-74. PMID: 12925201 4. Abe-Dohmae, S. et al. (2004) The Journal of biological chemistry 279, 604-11. PMID: 14570867 5. Ikeda, Y. et al. (2003) Biochemical and biophysical research communications 311, 313-8. PMID: 14592415 |
| Note | For research use only. |

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