

| 货号 | HP309014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ASH2L (Met430-Pro628). | ||||||||
| 靶标 | ASH2L, ASH2-like protein, Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2L1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9UBL3 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2L) is a ~68 kDa protein. Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. 1. Wysocka, J. et al. (2003) Genes & development 17, 896-911. PMID: 12670868 2. Garapaty, S. et al. (2009) The Journal of biological chemistry 284, 7542-52. PMID: 19131338 3. Patel, A. et al. (2009) The Journal of biological chemistry 284, 24242-56. PMID: 19556245 4. Avdic, V. et al. (2011) Structure (London, England : 1993) 19, 101-8. PMID: 21220120 5. Zhang, P. et al. (2012) Nucleic acids research 40, 4237-46. PMID: 22266653 | ||||||||
| Note | For research use only. |

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