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Anti-Human ASH2L Polyclonal Antibody (ARO-A12054)

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概述
货号ARO-A12054
品牌ProteoGenix
描述
Anti-Human ASH2L Polyclonal Antibody (ARO-A12054) is a rabbit polyclonal antibody detecting ASH2L, ASH2-like protein, Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2L1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ASH2L (Met430-Pro628).
靶标ASH2L, ASH2-like protein, Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2L1
纯化方式Purified by antigen affinity column.
Accession号Q9UBL3
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2L) is a ~68 kDa protein. Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis.

1. Wysocka, J. et al. (2003) Genes & development 17, 896-911. PMID: 12670868
2. Garapaty, S. et al. (2009) The Journal of biological chemistry 284, 7542-52. PMID: 19131338
3. Patel, A. et al. (2009) The Journal of biological chemistry 284, 24242-56. PMID: 19556245
4. Avdic, V. et al. (2011) Structure (London, England : 1993) 19, 101-8. PMID: 21220120
5. Zhang, P. et al. (2012) Nucleic acids research 40, 4237-46. PMID: 22266653
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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