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Anti-Human SNX5 Polyclonal Antibody (HP226014)

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概述
货号HP226014
品牌abinScience
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SNX5 (Met1-Asp171).
靶标SNX5, Sorting nexin-5
纯化方式Purified by antigen affinity column.
Accession号Q9Y5X3
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Sorting nexin-5 (SNX5) is a ~46 kDa protein. Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable).

1. Merino-Trigo, A. et al. (2004) Journal of cell science 117, 6413-24. PMID: 15561769
2. van Weering, JR. et al. (2012) The EMBO journal 31, 4466-80. PMID: 23085988
3. Wassmer, T. et al. (2007) Journal of cell science 120, 45-54. PMID: 17148574
4. Hara, S. et al. (2008) Molecular biology of the cell 19, 3823-35. PMID: 18596235
5. Sun, Y. et al. (2013) Developmental cell 25, 144-55. PMID: 23602387
6. Schill, NJ. et al. (2014) Journal of cell science 127, 2189-203. PMID: 24610942
7. Lim, JP. et al. (2008) BMC cell biology 9, 58. PMID: 18854019
8. Wang, JT. et al. (2010) PloS one 5, e13763. PMID: 21048941
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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