

| 货号 | ARO-A11992 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human SNX5 Polyclonal Antibody (ARO-A11992) is a rabbit polyclonal antibody detecting SNX5, Sorting nexin-5 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human SNX5 (Met1-Asp171). |
| 靶标 | SNX5, Sorting nexin-5 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9Y5X3 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Sorting nexin-5 (SNX5) is a ~46 kDa protein. Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). 1. Merino-Trigo, A. et al. (2004) Journal of cell science 117, 6413-24. PMID: 15561769 2. van Weering, JR. et al. (2012) The EMBO journal 31, 4466-80. PMID: 23085988 3. Wassmer, T. et al. (2007) Journal of cell science 120, 45-54. PMID: 17148574 4. Hara, S. et al. (2008) Molecular biology of the cell 19, 3823-35. PMID: 18596235 5. Sun, Y. et al. (2013) Developmental cell 25, 144-55. PMID: 23602387 6. Schill, NJ. et al. (2014) Journal of cell science 127, 2189-203. PMID: 24610942 7. Lim, JP. et al. (2008) BMC cell biology 9, 58. PMID: 18854019 8. Wang, JT. et al. (2010) PloS one 5, e13763. PMID: 21048941 |
| Note | For research use only. |

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