Anti-Human KDM6B Polyclonal Antibody (HT282014)

价格:

规格：

50ug
100ug

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

HT282014

abinScience

种属反应性

Human, Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human KDM6B (Pro1186-Arg1643).

JMJD3, [histone H3]-trimethyl-L-lysine(27) demethylase 6B, Jumonji domain-containing protein 3, KDM6B, JmjC domain-containing protein 3, KIAA0346, Lysine demethylase 6B, Lysine-specific demethylase 6B

Purified by antigen affinity column.

Accession号

O15054

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Lysine-specific demethylase 6B (KDM6B) is a ~176 kDa protein. Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex.

1. Agger, K. et al. (2007) Nature 449, 731-4. PMID: 17713478

2. De Santa, F. et al. (2007) Cell 130, 1083-94. PMID: 17825402

3. Lan, F. et al. (2007) Nature 449, 689-94. PMID: 17851529

4. Hong, S. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 18439-44. PMID: 18003914

For research use only.

产品说明书

Anti-Human KDM6B Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KDM6B Polyclonal Antibody (HT282014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KDM6B Polyclonal Antibody (HT282014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价