Anti-Human KDM6B IP Recombinant Antibody (SAA0207) (HT282013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HT282013

abinScience

种属反应性

Human

ELISA, IF, IP

IgG2a

SAA0207

JMJD3, [histone H3]-trimethyl-L-lysine(27) demethylase 6B, Jumonji domain-containing protein 3, KDM6B, JmjC domain-containing protein 3, KIAA0346, Lysine demethylase 6B, Lysine-specific demethylase 6B

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O15054

Anti-Human KDM6B IP Antibody (SAA0207) (abinScience Cat# HT282013, RRID:AB_3729741)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Lysine-specific demethylase 6B (KDM6B) is a ~176 kDa protein. Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex.

1. Agger, K. et al. (2007) Nature 449, 731-4. PMID: 17713478

2. De Santa, F. et al. (2007) Cell 130, 1083-94. PMID: 17825402

3. Lan, F. et al. (2007) Nature 449, 689-94. PMID: 17851529

4. Hong, S. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 18439-44. PMID: 18003914

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

SDS-PAGE

SDS-PAGE for Anti-Human KDM6B IP Antibody (SAA0207).

产品说明书

Anti-Human KDM6B IP Recombinant Antibody (SAA0207).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KDM6B IP Recombinant Antibody (SAA0207) (HT282013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KDM6B IP Recombinant Antibody (SAA0207) (HT282013)

概述

图片

参考文献

产品说明书

相关产品推荐

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