

| 货号 | HB608014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human NMT1 (Thr108-Gln496). | ||||||||
| 靶标 | Myristoyl-CoA:protein N-myristoyltransferase 1, Type I N-myristoyltransferase, NMT 1, Peptide N-myristoyltransferase 1, NMT1, Glycylpeptide N-tetradecanoyltransferase 1, NMT | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P30419 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) is a ~56 kDa protein. Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle. 1. Montgomery, C. et al. (2012) The Journal of biological chemistry 287, 33227-36. PMID: 22865860 2. Thinon, E. et al. (2014) Nature communications 5, 4919. PMID: 25255805 3. Chen, YC. et al. (2020) Scientific reports 10, 11952. PMID: 32686708 4. Sun, Y. et al. (2022) Cancer letters 529, 126-138. PMID: 34999170 5. Glover, CJ. et al. (1997) The Journal of biological chemistry 272, 28680-9. PMID: 9353336 6. Giang, DK. et al. (1998) The Journal of biological chemistry 273, 6595-8. PMID: 9506952 7. Kosciuk, T. et al. (2020) Nature communications 11, 1067. PMID: 32103017 8. Dian, C. et al. (2020) Nature communications 11, 1132. PMID: 32111831 | ||||||||
| Note | For research use only. |

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