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Anti-Human NMT1 Polyclonal Antibody (ARO-A11978)

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概述
货号ARO-A11978
品牌ProteoGenix
描述
Anti-Human NMT1 Polyclonal Antibody (ARO-A11978) is a rabbit polyclonal antibody detecting Myristoyl-CoA:protein N-myristoyltransferase 1, Type I N-myristoyltransferase, NMT 1, Peptide N-myristoyltransferase 1, NMT1, Glycylpeptide N-tetradecanoyltransferase 1, NMT in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human NMT1 (Thr108-Gln496).
靶标Myristoyl-CoA:protein N-myristoyltransferase 1, Type I N-myristoyltransferase, NMT 1, Peptide N-myristoyltransferase 1, NMT1, Glycylpeptide N-tetradecanoyltransferase 1, NMT
纯化方式Purified by antigen affinity column.
Accession号P30419
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) is a ~56 kDa protein. Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle.

1. Montgomery, C. et al. (2012) The Journal of biological chemistry 287, 33227-36. PMID: 22865860
2. Thinon, E. et al. (2014) Nature communications 5, 4919. PMID: 25255805
3. Chen, YC. et al. (2020) Scientific reports 10, 11952. PMID: 32686708
4. Sun, Y. et al. (2022) Cancer letters 529, 126-138. PMID: 34999170
5. Glover, CJ. et al. (1997) The Journal of biological chemistry 272, 28680-9. PMID: 9353336
6. Giang, DK. et al. (1998) The Journal of biological chemistry 273, 6595-8. PMID: 9506952
7. Kosciuk, T. et al. (2020) Nature communications 11, 1067. PMID: 32103017
8. Dian, C. et al. (2020) Nature communications 11, 1132. PMID: 32111831
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human NMT1 Polyclonal Antibody

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