

| 货号 | HT314014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-SCO2 Polyclonal Antibody (HT314014) is a rabbit polyclonal antibody detecting SCO2 in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human SCO2 (Gly42-Ser266). | ||||||||
| 靶标 | Protein SCO2 homolog, mitochondrial, SCO2 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O43819 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Cytochrome c oxidase assembly factor SCO2 is a ~29 kDa protein. Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2); together with SCO1, facilitates the incorporation of copper into the Cu(A) site of MT-CO2/COX2. Could also act as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2. 1. Leary, SC. et al. (2004) Human molecular genetics 13, 1839-48. PMID: 15229189 2. Leary, SC. et al. (2007) Cell metabolism 5, 9-20. PMID: 17189203 3. Leary, SC. et al. (2009) Human molecular genetics 18, 2230-40. PMID: 19336478 4. Nývltová, E. et al. (2022) Nature communications 13, 3615. PMID: 35750769 | ||||||||
| Note | For research use only. |

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