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Anti-SCO2 Polyclonal Antibody (ARO-A14331)

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概述
货号ARO-A14331
品牌ProteoGenix
描述
Anti-SCO2 Polyclonal Antibody (ARO-A14331) is a rabbit polyclonal antibody detecting Protein SCO2 homolog, mitochondrial, SCO2 in ELISA, IHC, WB. Suitable for Bos taurus, Human, Mouse.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Bos taurus, Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human SCO2 (Gly42-Ser266).
靶标Protein SCO2 homolog, mitochondrial, SCO2
纯化方式Purified by antigen affinity column.
Accession号O43819
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Cytochrome c oxidase assembly factor SCO2 is a ~29 kDa protein. Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2); together with SCO1, facilitates the incorporation of copper into the Cu(A) site of MT-CO2/COX2. Could also act as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.

1. Leary, SC. et al. (2004) Human molecular genetics 13, 1839-48. PMID: 15229189
2. Leary, SC. et al. (2007) Cell metabolism 5, 9-20. PMID: 17189203
3. Leary, SC. et al. (2009) Human molecular genetics 18, 2230-40. PMID: 19336478
4. Nývltová, E. et al. (2022) Nature communications 13, 3615. PMID: 35750769
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-SCO2 Polyclonal Antibody

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