

| 货号 | HF536014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ACSL3 (Lys581-Lys720). | ||||||||
| 靶标 | LACS 3, LACS3, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 3, ACS3, Long-chain-fatty-acid--CoA ligase 3, FACL3, ACSL3 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O95573 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Fatty acid CoA ligase Acsl3 is a ~80 kDa protein. Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. 1. Nakahara, K. et al. (2012) Molecular cell 46, 461-71. PMID: 22633490 2. Yao, H. et al. (2008) The Journal of biological chemistry 283, 849-54. PMID: 18003621 | ||||||||
| Note | For research use only. |

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