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Anti-Human ACSL3 Polyclonal Antibody (ARO-A11915)

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概述
货号ARO-A11915
品牌ProteoGenix
描述
Anti-Human ACSL3 Polyclonal Antibody (ARO-A11915) is a rabbit polyclonal antibody detecting LACS 3, LACS3, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 3, ACS3, Long-chain-fatty-acid--CoA ligase 3, FACL3, ACSL3 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ACSL3 (Lys581-Lys720).
靶标LACS 3, LACS3, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 3, ACS3, Long-chain-fatty-acid--CoA ligase 3, FACL3, ACSL3
纯化方式Purified by antigen affinity column.
Accession号O95573
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Fatty acid CoA ligase Acsl3 is a ~80 kDa protein. Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates.

1. Nakahara, K. et al. (2012) Molecular cell 46, 461-71. PMID: 22633490
2. Yao, H. et al. (2008) The Journal of biological chemistry 283, 849-54. PMID: 18003621
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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