Anti-Human RAB3IP Polyclonal Antibody (HP867014)

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规格：

50ug
100ug

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概述
图片
参考文献
产品说明书

HP867014

abinScience

种属反应性

Human

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human RAB3IP (Asp314-Leu476).

Rabin-3, Rab3A-interacting protein, Rab-3A-interacting protein, SSX2-interacting protein, RAB3IP, RABIN8

Purified by antigen affinity column.

Accession号

Q96QF0

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Rab-3A-interacting protein (RAB3IP) is a ~53 kDa protein. Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

1. Hattula, K. et al. (2002) Molecular biology of the cell 13, 3268-80. PMID: 12221131

2. Steger, M. et al. (2016) eLife 5. PMID: 26824392

3. Yoshimura, S. et al. (2010) The Journal of cell biology 191, 367-81. PMID: 20937701

4. Bryant, DM. et al. (2010) Nature cell biology 12, 1035-45. PMID: 20890297

5. Wang, J. et al. (2015) Journal of cell science 128, 1375-85. PMID: 25673879

6. Walia, V. et al. (2019) Developmental cell 50, 229-246.e7. PMID: 31204173

For research use only.

产品说明书

Anti-Human RAB3IP Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RAB3IP Polyclonal Antibody (HP867014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RAB3IP Polyclonal Antibody (HP867014)

概述

图片

参考文献

产品说明书

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