Anti-Human NXF1 Polyclonal Antibody (HP062014)

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规格：

50ug
100ug

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概述
图片
参考文献
产品说明书

HP062014

abinScience

种属反应性

Human, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human NXF1 (Lys205-Lys347).

mRNA export factor TAP, Nuclear RNA export factor 1, Tip-associating protein, TAP, Tip-associated protein, NXF1

Purified by antigen affinity column.

Accession号

Q9UBU9

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Nuclear RNA export factor 1 (NXF1) is a ~70 kDa protein. Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export.

1. Tang, H. et al. (2000) The Journal of biological chemistry 275, 32694-700. PMID: 10924507

2. Hautbergue, GM. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 5154-9. PMID: 18364396

3. Katahira, J. et al. (2009) The EMBO journal 28, 556-67. PMID: 19165146

4. Grüter, P. et al. (1998) Molecular cell 1, 649-59. PMID: 9660949

5. Roundtree, IA. et al. (2017) eLife 6. PMID: 28984244

For research use only.

产品说明书

Anti-Human NXF1 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NXF1 Polyclonal Antibody (HP062014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NXF1 Polyclonal Antibody (HP062014)

概述

图片

参考文献

产品说明书

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