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Anti-Human NXF1 Polyclonal Antibody (ARO-A11854)

概述
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参考文献

概述

货号	ARO-A11854
品牌	ProteoGenix
描述	Anti-Human NXF1 Polyclonal Antibody (ARO-A11854) is a rabbit polyclonal antibody detecting mRNA export factor TAP, Nuclear RNA export factor 1, Tip-associating protein, TAP, Tip-associated protein, NXF1 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human NXF1 (Lys205-Lys347).
靶标	mRNA export factor TAP, Nuclear RNA export factor 1, Tip-associating protein, TAP, Tip-associated protein, NXF1
纯化方式	Purified by antigen affinity column.
Accession号	Q9UBU9
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Nuclear RNA export factor 1 (NXF1) is a ~70 kDa protein. Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export. 1. Tang, H. et al. (2000) The Journal of biological chemistry 275, 32694-700. PMID: 10924507 2. Hautbergue, GM. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 5154-9. PMID: 18364396 3. Katahira, J. et al. (2009) The EMBO journal 28, 556-67. PMID: 19165146 4. Grüter, P. et al. (1998) Molecular cell 1, 649-59. PMID: 9660949 5. Roundtree, IA. et al. (2017) eLife 6. PMID: 28984244
Note	For research use only.

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公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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质量

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浓度

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体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

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V₁ (起始体积)

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工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-Human NXF1 Polyclonal Antibody

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