Anti-Human TRIM11 Polyclonal Antibody (HP506014)

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50ug
100ug

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HP506014

abinScience

种属反应性

Human, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human TRIM11 (Asn297-Arg456).

Tripartite motif-containing protein 11, RING-type E3 ubiquitin transferase TRIM11, TRIM11, RING finger protein 92, RNF92, E3 ubiquitin-protein ligase TRIM11, Protein BIA1

Purified by antigen affinity column.

Accession号

Q96F44

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

E3 ubiquitin-protein ligase TRIM11 is a ~52 kDa protein. E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation.

1. Ishikawa, H. et al. (2006) FEBS letters 580, 4784-92. PMID: 16904669

2. Uchil, PD. et al. (2008) PLoS pathogens 4, e16. PMID: 18248090

3. Liu, T. et al. (2016) Cell reports 16, 1988-2002. PMID: 27498865

For research use only.

产品说明书

Anti-Human TRIM11 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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Anti-Human TRIM11 Polyclonal Antibody (HP506014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TRIM11 Polyclonal Antibody (HP506014)

概述

图片

参考文献

产品说明书

相关产品推荐

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