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Anti-Human TRIM11 Polyclonal Antibody (ARO-A11814)

概述
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参考文献

概述

货号	ARO-A11814
品牌	ProteoGenix
描述	Anti-Human TRIM11 Polyclonal Antibody (ARO-A11814) is a rabbit polyclonal antibody detecting Tripartite motif-containing protein 11, RING-type E3 ubiquitin transferase TRIM11, TRIM11, RING finger protein 92, RNF92, E3 ubiquitin-protein ligase TRIM11, Protein BIA1 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human TRIM11 (Asn297-Arg456).
靶标	Tripartite motif-containing protein 11, RING-type E3 ubiquitin transferase TRIM11, TRIM11, RING finger protein 92, RNF92, E3 ubiquitin-protein ligase TRIM11, Protein BIA1
纯化方式	Purified by antigen affinity column.
Accession号	Q96F44
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	E3 ubiquitin-protein ligase TRIM11 is a ~52 kDa protein. E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. 1. Ishikawa, H. et al. (2006) FEBS letters 580, 4784-92. PMID: 16904669 2. Uchil, PD. et al. (2008) PLoS pathogens 4, e16. PMID: 18248090 3. Liu, T. et al. (2016) Cell reports 16, 1988-2002. PMID: 27498865
Note	For research use only.

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公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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体积

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公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

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V₁ (起始体积)

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工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-Human TRIM11 Polyclonal Antibody

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