

| 货号 | HW319014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PDE6B (Met1-Gly198). | ||||||||
| 靶标 | GMP-PDE beta, PDEB, Rod cGMP-specific 3', 5'-cyclic phosphodiesterase subunit beta, PDE6B | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P35913 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (PDE6B) is a ~98 kDa protein. Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. Necessary for the formation of a functional phosphodiesterase holoenzyme. Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock. May participate in processes of transmission and amplification of the visual signal. 1. Muradov, H. et al. (2010) The Journal of biological chemistry 285, 39828-34. PMID: 20940301 2. McLaughlin, ME. et al. (1993) Nature genetics 4, 130-4. PMID: 8394174 | ||||||||
| Note | For research use only. |

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