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Anti-Human PDE6B Polyclonal Antibody (PTX20277)

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概述
货号PTX20277
品牌ProteoGenix
描述
Anti-Human PDE6B Polyclonal Antibody (PTX20277) is a rabbit polyclonal antibody detecting GMP-PDE beta, PDEB, Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, PDE6B in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PDE6B (Met1-Gly198).
靶标GMP-PDE beta, PDEB, Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, PDE6B
纯化方式Purified by antigen affinity column.
Accession号P35913
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (PDE6B) is a ~98 kDa protein. Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. Necessary for the formation of a functional phosphodiesterase holoenzyme. Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock. May participate in processes of transmission and amplification of the visual signal.

1. Muradov, H. et al. (2010) The Journal of biological chemistry 285, 39828-34. PMID: 20940301
2. McLaughlin, ME. et al. (1993) Nature genetics 4, 130-4. PMID: 8394174
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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