Anti-CYGB Polyclonal Antibody (HV972024)

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规格：

50ug
100ug

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HV972024

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Human CYGB (Met1-Lys111).

Histoglobin, CYGB, Stellate cell activation-associated protein, Cytoglobin, STAP, HGb

Purified by antigen affinity column.

Accession号

Q8WWM9

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Cytoglobin (CYGB) is a ~21 kDa protein. Probable multifunctional globin with a hexacoordinated heme iron required for the catalysis of various reactions depending on redox condition of the cell as well as oxygen availability. Has a nitric oxide dioxygenase (NOD) activity and is most probably involved in cell-mediated and oxygen-dependent nitric oxide consumption. By scavenging this second messenger may regulate several biological processes including endothelium-mediated vasodilation and vascular tone. Under normoxic conditions functions as a nitric oxide dioxygenase (NOD) but under hypoxic conditions the globin may switch its function to that of a nitrite (NO2) reductase (NiR), generating nitric oxide. Could also have peroxidase and superoxide dismutase activities, detoxifying reactive oxygen species and protecting cells against oxidative stress.

1. Trent, JT. et al. (2002) The Journal of biological chemistry 277, 19538-45. PMID: 11893755

2. Asahina, K. et al. (2002) Biochimica et biophysica acta 1577, 471-5. PMID: 12359339

3. Sugimoto, H. et al. (2004) Journal of molecular biology 339, 873-85. PMID: 15165856

4. Halligan, KE. et al. (2009) The Journal of biological chemistry 284, 8539-47. PMID: 19147491

5. Gardner, AM. et al. (2010) The Journal of biological chemistry 285, 23850-7. PMID: 20511233

6. Liu, X. et al. (2017) Nature communications 8, 14807. PMID: 28393874

7. Amdahl, MB. et al. (2017) Biochemistry 56, 3993-4004. PMID: 28671819

8. Reeder, BJ. et al. (2018) Nitric oxide : biology and chemistry 72, 16-23. PMID: 29128400

9. Dat, NQ. et al. (2021) Hepatology (Baltimore, Md.) 73, 2527-2545. PMID: 33576020

10. Zweier, JL. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 34930834

For research use only.

产品说明书

Anti-CYGB Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CYGB Polyclonal Antibody (HV972024)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CYGB Polyclonal Antibody (HV972024)

概述

图片

参考文献

产品说明书

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