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Anti-Human OSBPL2 Polyclonal Antibody (HP845014)

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概述
货号HP845014
品牌abinScience
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human OSBPL2 (Ala96-Asp325).
靶标ORP-2, Oxysterol-binding protein-related protein 2, ORP2, OSBPL2, KIAA0772, OSBP-related protein 2
纯化方式Purified by antigen affinity column.
Accession号Q9H1P3
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Oxysterol-binding protein-related protein 2 (OSBPL2) is a ~55 kDa protein. Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro).

1. Wang, H. et al. (2019) Molecular cell 73, 458-473.e7. PMID: 30581148
2. Xu, Y. et al. (2001) The Journal of biological chemistry 276, 18407-14. PMID: 11279184
3. Suchanek, M. et al. (2007) The Biochemical journal 405, 473-80. PMID: 17428193
4. Hynynen, R. et al. (2009) Journal of lipid research 50, 1305-15. PMID: 19224871
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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